ASSOCIATION OF URIC ACID WITH PREECLAMPSIA

Objective: Objective of this study is to associate the elevated level of uric acid with preeclampsia.
Methods: this was cross sectional analytical study conducted in Gynae/obs department of Hayatabad Medical Complex
Peshawar, during June 2015 to December 2015. A total of 200 pregnant (100 pre-eclamptic 100 normotensive)
pregnant women of the same gestational age and parity included in the study. A 5mL of venous blood was processed
for determination of uric acid. Uric acid levels were measured by uricase enzyme based calorimetric method. Student
T-test was applied for comparative aspects
Results: Mean and standard deviation for uric acid, systolic and diastolic blood pressure, were highly significant
(p<0.000) in preeclampsia women as compare to control group. Mean and standard value for uric acid is 5.97 ± 1.86
in patients and 4.04 ± 1.43mg/dl in control group, were highly significant (p<0.000).
Conclusion: Uric acid shows significant correlation with systolic and diastolic blood pressure and is a better predictor
of PE and eclampsia.