EVALUATION OF EARLY VERSUS DELAYED LAPAROSCOPIC CHOLECYSTECTOMY IN ACUTE CHOLECYSTITIS: A PROSPECTIVE RANDOMISED STUDY

ABSTRACT
Background: Laparoscopic cholecystectomy has revolutionised the treatment of this disorder significantly. Current
trends are investigating the effectiveness of early intervention in this subset of patients.
Methods: After the institute’s research evaluation committee approval, the study was conducted prospectively at
department of General and laparoscopic surgery of Hayatabad Medical Complex Peshawar from June 2014 to June
2015. Preoperative clinical features, intraoperative findings and postoperative outcome was recorded. The data was
analysed using IBM SPSS version 22.0.
Results: 100 patients, 54 in ELC group & 46 in DLC group with mean age 48.32 years ± 11.019 SD. The mean procedure
time was 61.20 minutes ± 9.809 SD. Mean procedure time for ELC was 62.13 minutes ± 9.711 SD while 60.11 minutes
± 9.916 forDLC (between goups ANOVA; p = 0.307). Neither procedure was associated with statistically significant
benefits in terms of LOS, complications or overall outcome (p = 0.58; OR= 0.944, 95% CI: 0.767-1.161).
Conclusions: For the management of acute cholecystitis, both early or delayed laparoscopic cholecystectomy are
safe options with less complications and good overall outcome.
Keywords: Laparoscopy, Cholecystectomy, Early, Delayed intervention, Complications