FREQUENCY OF COMMON HEMATOLOGICAL DISEASES IN PAEDIATRIC PATIENTS PRESENTING WITH CLINICAL FEATURES INDICATIVE OF BONE MARROW EXAMINATION

ABSTRACT
Objective: The objective of the study was to find the frequency of common hematological diseases diagnosed on bone
marrow examination in our pediatric age group of patients.
Material and Methods: This study was conducted in the haematology unit, department of pathology, past medical
graduate institute(PGMI), Hayatabad Medical Complex Peshawar (HMC)from March 1st 2012 to Jan 23rd 2013. Children
admitted with bleeding, lymphadenopathy, Splenomegaly, Hepatomegaly, isolated or pancytopenia on peripheral
blood smear was included in this study. The data was statistically analyzed by SPSS version 10.
Results: One hundred and sixty three cases were included in this study. The age range was from >1 month to15 years
with a mean age of 6.56 years and standard deviation of + 4.668. Majority 82 (50.3%) of the children were in the age
range of 1to 5 years. Male to female ratio was1.39:1. The commonest disorder was leukemia present in 65(39.9%)of
the cases followed by megaloblastic anemia present in 25(15.3%)cases, idiopathic thrombocytopenic purpura(ITP)
present in 18(11%) cases and aplastic anemia present in 11(6.7%) cases.
Conclusion: leukemia followed by megaloblastic anemia were the common most haematological disorders, most
commonly found in males of age group 1year to 5 years.
Key Words: Bone marrow Examination, Leukemia, Megaloblastic anemia, Aplastic Anemia, Idiopathic Thrombocytopenic
Purpura (ITP)