FREQUENCY OF CARCINOMA PROSTATE IN TURP SPECIMEN IN PATIENT WITH CLINICALLY BENIGN PROSTATIC HYPERPLASIA WITH PSA LESS THAN 4NG/ML

ABSTRACT
Material and Method: Study was conducted at institute of kidney disease hayatabad medical complex from March
2013 to march 2015. All patients meeting the criteria i.e. men of 50year and above with LUTS due to enlarged prostate,
PSA less than 4ng/ml, prostate size less than 100gm, was enrolled in the study and TURP specimen were sent for
histopathology to determine the frequency of prostate adenocarcinomas.
Results: In this study, 139 patients with clinically benign prostatic hyperplasia with Prostate specific antigen less than
4ng/ml had observed, in which 68(48.92%) patients have prostate specific antigen(PSA) level were less than or equal to
2 and 71(51.08%) patients have more than 2. Patients age was divided in four categories, out of which most presented
in 56-65 years which were 50(36%) while 22(15.8%) patients were in the age range of less than 55 years, 37(26.6%)
were of age rang 66-75 years and 30(21.6%) presented at age more than75 years. The study included age ranged from
50 up to 79 years. Average age was 65.50 years + 8.78SD. Overall Carcinoma prostate among patients presenting
with clinically benign prostatic hyperplasia was 18(12.95%) while 121(87.05%) were found non Carcinoma prostate.
Conclusion: The incidence of Carcinoma prostate among patients with clinically benign prostatic hyperplasia with
Prostate specific antigen less than 4ng/ml is quite high. The foremost thing is to create awareness among the masses
to seek medical help for proper evaluation and diagnosis so that adequate treatment can be initiated at an earlier stage