DETERMINATION OF SERUM CREATININE FOR PREDICTION OF PRE ECLAMPSIA

Objective: Objective of this study is the determination of serum creatinine in gestational hypertension specifically preeclampsia
and compare it with normal pregnant women of same gestational age,and to assess its role in preeclampsia.
Study design: Cross sectional analytical.
Methodology: This cross sectional study involved 100 pre-eclamptic pregnant women and 100 normotensive pregnant
women of the same gestational age and parity for determination of serum creatinine, from the period of June 2015 to
December 2015,involving the outpatients and admitted patients in Gynae/obs department of Lady Reading hospital
and Hayatabad Medical Complex Peshawar,Khyber pukhtunkhwa.
Results: Mean and standard deviation for serum creatinine, systolic and diastolic blood pressure, were highly significant
(p<0.000) in pre-eclampsia women as compare to control group. Mean and standard value for serum creatinine 0.72
± 0 .20 in patients and 0.62 ± 0.10mg/dl in control group, were highly significant (p<0.000).
Conclusion: Serum creatinine shows significant correlation with systolic and diastolic blood pressure and may be
helpful for early diagnosis and management of pre–eclampsia in order to prevent fetal and maternal complications due
to pre-eclampsia(PE) and eclampsia